Dr. Edward Fruitman, M.D., explains why ketamine therapy is considered a safe and effective option for individuals struggling with treatment-resistant depression.

While the exact way ketamine works is still being studied, it is known to affect the brain’s glutamate system (NMDA receptors) — one of the most important and widespread neurotransmitter systems involved in mood regulation and brain function.

Leading research institutions continue to study ketamine’s potential, with growing evidence supporting its role in helping patients who have not responded to traditional depression treatments. At Trifecta Health, we believe in providing innovative, evidence-based care tailored to each patient’s needs.